5P2P
X-RAY STRUCTURE OF PHOSPHOLIPASE A2 COMPLEXED WITH A SUBSTRATE-DERIVED INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PHOSPHOLIPASE A2 | polymer | 119 | 13431.0 | 2 | UniProt (P00592) Pfam (PF00068) | Sus scrofa (pig) | |
| 2 | C, E, F (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | D, G (A, B) | PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER | non-polymer | 423.5 | 2 | Chemie (DHG) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 124 (UniProt: P00592)
| PDB | External Database | Details |
|---|---|---|
| Phe 3 | Trp 25 | conflict |
| Trp 31 | Leu 53 | conflict |
| Ser 59 | Asp 81 | conflict |
| Gly 60 | Ser 82 | conflict |
| - | Lys 84 | deletion |
| - | Phe 85 | deletion |
| - | Leu 86 | deletion |
| - | Val 87 | deletion |
| - | Asp 88 | deletion |
| Tyr 67 | Asn 89 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26862.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 967.3 | |
| All* | Total formula weight | 27829.3 |
