5OWR
Human STK10 bound to dasatinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 10 | polymer | 302 | 34298.6 | 1 | UniProt (O94804) Pfam (PF00069) | Homo sapiens (Human) | Lymphocyte-oriented kinase |
| 2 | B (A) | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | non-polymer | 488.0 | 1 | Chemie (1N1) | |||
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (A) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A: 18 - 317 (UniProt: O94804)
| PDB | External Database | Details |
|---|---|---|
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34298.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 528.1 | |
| All* | Total formula weight | 34826.7 |
