5OW1
X-Ray Characterization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 5 | polymer | 305 | 35236.9 | 1 | UniProt (P54829) Pfam (PF00102) In PDB | Homo sapiens (Human) | Neural-specific protein-tyrosine phosphatase,Striatum-enriched protein-tyrosine phosphatase,STEP |
2 | A | [[3-(3-cyclohexyl-2-oxidanyl-phenyl)phenyl]-bis(fluoranyl)methyl]phosphonic acid | non-polymer | 382.3 | 1 | Chemie (AY8) | |||
3 | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A: 258 - 539 (UniProt: P54829)
PDB | External Database | Details |
---|---|---|
Met 235 | - | initiating methionine |
His 236 | - | expression tag |
His 237 | - | expression tag |
His 238 | - | expression tag |
His 239 | - | expression tag |
His 240 | - | expression tag |
His 241 | - | expression tag |
Ser 242 | - | expression tag |
Ser 243 | - | expression tag |
Gly 244 | - | expression tag |
Val 245 | - | expression tag |
Asp 246 | - | expression tag |
Leu 247 | - | expression tag |
Gly 248 | - | expression tag |
Thr 249 | - | expression tag |
Glu 250 | - | expression tag |
Asn 251 | - | expression tag |
Leu 252 | - | expression tag |
Tyr 253 | - | expression tag |
Phe 254 | - | expression tag |
Gln 255 | - | expression tag |
Ser 256 | - | expression tag |
Met 257 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35236.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 382.3 | |
All* | Total formula weight | 35619.2 |