5OVB
Crystal structure of human BRD4(1) bromodomain in complex with DR46
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 2 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A, B | ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(1-methylpyrazol-3-yl)phenyl]furan-2-carboxamide | non-polymer | 429.5 | 2 | Chemie (AY2) | |||
3 | water | water | 18.0 | 387 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 168 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Ser 42 | - | expression tag |
Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30198.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 858.9 | |
All* | Total formula weight | 31057.7 |