5OUC
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp191 and RKp190
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41193.7 | 1 | UniProt (P25321) Pfam (PF00069) In PDB | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
2 | E | cAMP-dependent protein kinase inhibitor | polymer | 18 | 1989.2 | 1 | UniProt (by SIFTS) (G3HK48) In PDB | Cricetulus griseus | |
3 | A | [2-[[2-(isoquinolin-5-ylsulfonylamino)ethylamino]methyl]phenyl]boronic acid | non-polymer | 385.2 | 1 | Chemie (AO8) | |||
4 | E | beta-D-ribopyranose | non-polymer | 150.1 | 1 | Chemie (RIP) | |||
5 | E | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43182.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 570.8 | |
All* | Total formula weight | 43753.8 |