5OTW
Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Cys
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (C, A) | Glucagon-like peptide 1 receptor | polymer | 116 | 13547.9 | 2 | UniProt (P43220) Pfam (PF02793) | Homo sapiens (Human) | GLP-1R |
| 2 | B, D (D, B) | Glucagon | polymer | 31 | 3407.8 | 2 | UniProt (P01275) Pfam (PF00123) | Homo sapiens | |
| 3 | E, F, G, H (C, D, A, B) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
D, B: 7 - 37 (UniProt: P01275)
| PDB | External Database | Details |
|---|---|---|
| Hcs 8 | Ala 99 | engineered mutation |
| Cys 11 | Thr 102 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 33911.4 | |
| All* | Total formula weight | 33911.4 |
