5OSY
Human Decapping Scavenger enzyme (hDcpS) in complex with m7G(5'S)ppSp(5'S)G mRNA 5' cap analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | m7GpppX diphosphatase | polymer | 301 | 34891.6 | 2 | UniProt (Q96C86) Pfam (PF05652) Pfam (PF11969) In PDB | Homo sapiens (Human) | DCS-1,Decapping scavenger enzyme,Hint-related 7meGMP-directed hydrolase,Histidine triad nucleotide-binding protein 5,Histidine triad protein member 5,HINT-5,Scavenger mRNA-decapping enzyme DcpS |
| 2 | A, B | [(2~{S},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl-[[[(2~{S},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl]oxy-phosphinic acid | non-polymer | 851.6 | 2 | Chemie (AJQ) | |||
| 3 | B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 467 | Chemie (HOH) |
Sequence modifications
A, B: 37 - 337 (UniProt: Q96C86)
| PDB | External Database | Details |
|---|---|---|
| Ser 37 | Cys 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69783.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2163.7 | |
| All* | Total formula weight | 71947.0 |
