5OSL
The crystal structure of CK2alpha in complex with compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Casein kinase II subunit alpha | polymer | 342 | 40786.4 | 1 | UniProt (P68400) Pfam (PF00069) In PDB | Homo sapiens (Human) | CK II alpha |
| 2 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | A | 2-[4-(aminomethyl)-2-chloranyl-phenyl]phenol | non-polymer | 233.7 | 2 | Chemie (A9K) | |||
| 6 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A: 2 - 329 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Ser 21 | Arg 21 | engineered mutation |
| Ala 74 | Lys 74 | engineered mutation |
| Ala 75 | Lys 75 | engineered mutation |
| Ala 76 | Lys 76 | engineered mutation |
| Arg 330 | - | expression tag |
| Glu 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Met 333 | - | expression tag |
| Glu 334 | - | expression tag |
| His 335 | - | expression tag |
| Pro 336 | - | expression tag |
| Tyr 337 | - | expression tag |
| Phe 338 | - | expression tag |
| Tyr 339 | - | expression tag |
| Thr 340 | - | expression tag |
| Val 341 | - | expression tag |
| Val 342 | - | expression tag |
| Lys 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40786.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1156.3 | |
| All* | Total formula weight | 41942.7 |
