Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 401 |
| Chain | Residue |
| A | ASP103 |
| A | ARG280 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | ARG80 |
| A | ARG155 |
| A | ASN189 |
| A | HOH578 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue ADP A 403 |
| Chain | Residue |
| A | LYS68 |
| A | ILE95 |
| A | GLU114 |
| A | VAL116 |
| A | HIS160 |
| A | ASN161 |
| A | MET163 |
| A | ILE174 |
| A | ASP175 |
| A | MG404 |
| A | MG405 |
| A | HOH502 |
| A | HOH503 |
| A | HOH577 |
| A | HOH596 |
| A | HOH604 |
| A | HOH613 |
| A | HOH644 |
| A | SER51 |
| A | VAL53 |
| A | VAL66 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 404 |
| Chain | Residue |
| A | ASP175 |
| A | ADP403 |
| A | HOH573 |
| A | HOH684 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 405 |
| Chain | Residue |
| A | ASN161 |
| A | ASP175 |
| A | ADP403 |
| A | HOH596 |
| A | HOH613 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue A9K A 406 |
| Chain | Residue |
| A | ASN118 |
| A | THR119 |
| A | LEU124 |
| A | LEU128 |
| A | MET137 |
| A | ILE140 |
| A | PRO159 |
| A | VAL162 |
| A | ILE164 |
| A | MET221 |
| A | MET225 |
| A | HOH512 |
| A | HOH598 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue A9K A 407 |
| Chain | Residue |
| A | GLU52 |
| A | ILE69 |
| A | PRO72 |
| A | SER106 |
| A | HOH504 |
| A | HOH535 |
| A | HOH641 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 408 |
| Chain | Residue |
| A | LYS158 |
| A | HIS160 |
| A | HOH596 |
| A | HOH613 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 33 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnekvvvkilkpv.AAAK |
| Chain | Residue | Details |
| A | LEU45-LYS77 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 285 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
