5OO6

Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J, M...	Nuclear cap-binding protein subunit 1	polymer	772	89810.0	8	UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) In PDB	Homo sapiens (Human)	80 kDa nuclear cap-binding protein,NCBP 80 kDa subunit
2	B, E, H, K, N...	Nuclear cap-binding protein subunit 2	polymer	158	18156.3	8	UniProt (P52298) Pfam (PF00076) In PDB	Homo sapiens (Human)	20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1
3	C, F, I, L, O...	Serrate RNA effector molecule homolog	polymer	48	5384.9	8	UniProt (Q9BXP5) In PDB	Homo sapiens (Human)	Arsenite-resistance protein 2
4	H, K, N, Q, T...	7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE	non-polymer		539.2	8	Chemie (MGT)

Sequence modifications

A, D, G, J, M, P, S, V: 20 - 790 (UniProt: Q09161)

PDB	External Database	Details
Met 19	-	initiating methionine
Val 479	Ala 479	conflict

B, E, H, K, N, Q, T, W: 1 - 156 (UniProt: P52298)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

C, F, I, L, O, R, U, X: 827 - 871 (UniProt: Q9BXP5)

PDB	External Database	Details
Gly 824	-	expression tag
Ala 825	-	expression tag
Met 826	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	906809.5
Non-Polymers*	Number of molecules	8
	Total formula weight	4313.8
All*	Total formula weight	911123.3

*Water molecules are not included.