5OM0
CH2 chimera of human 14-3-3 sigma with the Gli1 phosphopeptide around Ser640
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 14-3-3 protein sigma,Zinc finger protein GLI1 | polymer | 248 | 27810.1 | 2 | UniProt (P31947) UniProt (P08151) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin,Glioma-associated oncogene,Oncogene GLI |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A, B | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 4 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 231 (UniProt: P31947)
A, B: 237 - 245 (UniProt: P08151)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 77 | Lys 77 | engineered mutation |
| Gly 232 | - | linker |
| Ser 233 | - | linker |
| Gly 234 | - | linker |
| Ser 235 | - | linker |
| Leu 236 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55620.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 628.5 | |
| All* | Total formula weight | 56248.7 |
