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5OKM

Crystal structure of human SHIP2 Phosphatase-C2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2polymer46152750.58UniProt (O15357)Homo sapiens (Human)Inositol polyphosphate phosphatase-like protein 1,INPPL-1,Protein 51C,SH2 domain-containing inositol 5'-phosphatase 2,SHIP-2
2DA, EA, I, KA, P...
(E, F, A, H, B...)
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer282.37Chemie (B3P)
3J, V
(A, C)
NITRATE IONnon-polymer62.02Chemie (NO3)
4AA, BA, CA, FA, GA...
(D, F, G, A, H...)
1,2-ETHANEDIOLnon-polymer62.121Chemie (EDO)
5MA, NA, OA, PA, QA...
(A, B, C, D, E...)
waterwater18.01564Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 420 - 878 (UniProt: O15357)
PDBExternal DatabaseDetails
Gly 418-expression tag
Pro 419-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight422004.0
Non-Polymers*Number of molecules30
Total formula weight3403.8
All*Total formula weight425407.8
*Water molecules are not included.

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PDB entries from 2025-12-10

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