5OKI
Crystal structure of the Ctf18-1-8 module from Ctf18-RFC in complex with a 63 kDa fragment of DNA Polymerase epsilon
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA polymerase epsilon catalytic subunit A | polymer | 524 | 59749.2 | 2 | UniProt (P21951) Pfam (PF03104) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | DNA polymerase II subunit A |
| 2 | C, F (C, G) | Sister chromatid cohesion protein DCC1 | polymer | 380 | 44133.8 | 2 | UniProt (P25559) Pfam (PF09724) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Defective in sister chromatid cohesion protein 1 |
| 3 | D, G (D, H) | Chromosome transmission fidelity protein 8 | polymer | 133 | 15189.7 | 2 | UniProt (P38877) Pfam (PF09696) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 4 | E, H (E, I) | Chromosome transmission fidelity protein 18 | polymer | 26 | 3171.6 | 2 | UniProt (P49956) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Sequence modifications
A, B: 1 - 524 (UniProt: P21951)
| PDB | External Database | Details |
|---|---|---|
| Ala 290 | Asp 290 | engineered mutation |
| Ala 292 | Glu 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 244488.5 | |
| All* | Total formula weight | 244488.5 |
