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5OK9

CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with swapped phosphopeptides

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, E, F14-3-3 protein sigma,Heat shock protein beta-6polymer24627492.94UniProt (P31947)
UniProt (O14558)
Pfam (PF00244)
In PDB
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin,HspB6,Heat shock 20 kDa-like protein p20
2A, B, FDI(HYDROXYETHYL)ETHERnon-polymer106.15Chemie (PEG)
3waterwater18.0493Chemie (HOH)
Sequence modifications
A, B, E, F: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Ala 75Glu 75engineered mutation
Ala 76Glu 76engineered mutation
Ala 77Lys 77engineered mutation
Gly 232-linker
Ser 233-linker
Gly 234-linker
Ser 235-linker
A, B, E, F: 236 - 243 (UniProt: O14558)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight109971.6
Non-Polymers*Number of molecules5
Total formula weight530.6
All*Total formula weight110502.2
*Water molecules are not included.

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PDB entries from 2024-04-17

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