5OFV
Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 5-fluoro-2-methylbenzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | D-3-phosphoglycerate dehydrogenase | polymer | 223 | 23933.7 | 2 | UniProt (O43175) Pfam (PF00389) Pfam (PF02826) | Homo sapiens (Human) | 3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase |
| 2 | C, D (B, A) | 5-fluoranyl-2-methyl-benzoic acid | non-polymer | 154.1 | 2 | Chemie (9TZ) | |||
| 3 | E, F (B, A) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
B, A: 94 - 315 (UniProt: O43175)
| PDB | External Database | Details |
|---|---|---|
| Met 93 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47867.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 308.3 | |
| All* | Total formula weight | 48175.6 |
