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5OFB

Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation S87L

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
MORC family CW-type zinc finger protein 2polymer60670045.12UniProt (Q9Y6X9)
Pfam (PF13589)
Pfam (PF17942)
Pfam (PF07496)
Homo sapiens (Human)Zinc finger CW-type coiled-coil domain protein 1
2C, G
(B, A)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, H
(B, A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
4E, F, I
(B, A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5J, K
(B, A)
waterwater18.0304Chemie (HOH)
Sequence modifications
B, A: 1 - 603 (UniProt: Q9Y6X9)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Arg 0-expression tag
Leu 87Ser 87engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight140090.2
Non-Polymers*Number of molecules7
Total formula weight1218.1
All*Total formula weight141308.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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