5OEN
Crystal Structure of STAT2 in complex with IRF9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon regulatory factor 9 | polymer | 171 | 19100.7 | 1 | UniProt (Q61179) Pfam (PF10401) | Mus musculus (Mouse) | IRF-9,IFN-alpha-responsive transcription factor subunit,ISGF3 p48 subunit,Interferon-stimulated gene factor 3 gamma,ISGF-3 gamma,Transcriptional regulator ISGF3 subunit gamma |
| 2 | B (B) | Signal transducer and activator of transcription | polymer | 175 | 20238.4 | 1 | UniProt (Q3UDU1) Pfam (PF01017) | Mus musculus (Mouse) | |
| 3 | C, D (A, B) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 206 - 376 (UniProt: Q61179)
B: 141 - 315 (UniProt: Q3UDU1)
| PDB | External Database | Details |
|---|---|---|
| Ala 347 | Glu 347 | engineered mutation |
| Ala 348 | Glu 348 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 242 | Gln 242 | engineered mutation |
| Ala 243 | Lys 243 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39339.1 | |
| All* | Total formula weight | 39339.1 |
