5OC8
HDM2 (17-111, WILD TYPE) COMPLEXED WITH NVP-HDM201 AT 1.56A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase Mdm2 | polymer | 96 | 11156.1 | 1 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (Human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 2 | B (A) | (4~{S})-5-(5-chloranyl-1-methyl-2-oxidanylidene-pyridin-3-yl)-4-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one | non-polymer | 555.4 | 1 | Chemie (9QW) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A: 17 - 111 (UniProt: Q00987)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11156.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 590.9 | |
| All* | Total formula weight | 11746.9 |
