5OBG
Crystal structure of glycine binding protein in complex with strychnine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E (A, B, C, D, E) | Soluble acetylcholine receptor | polymer | 249 | 28309.7 | 5 | UniProt (Q8WSF8) Pfam (PF02931) | Aplysia californica (California sea hare) | |
2 | CA, F, LA, Q, XA (C, A, D, B, E) | STRYCHNINE | non-polymer | 334.4 | 5 | Chemie (SY9) | |||
3 | BA, BB, CB, DB, EA... (C, E, A, D, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 31 | Chemie (EDO) | |||
4 | IA, K, TA, UA, W (C, A, D, E, B) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
5 | AA, AB, JA, L, NA... (C, E, A, D, B) | ACETATE ION | non-polymer | 59.0 | 9 | Chemie (ACT) | |||
6 | DA, MA, R, YA (C, D, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
7 | HB, IB, JB, KB, LB (A, B, C, D, E) | water | water | 18.0 | 749 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 236 (UniProt: Q8WSF8)
PDB | External Database | Details |
---|---|---|
Phe 53 | Thr 53 | engineered mutation |
Val 60 | Ala 60 | conflict |
Arg 74 | Gln 74 | engineered mutation |
Ala 110 | Tyr 110 | engineered mutation |
Ser 135 | Ile 135 | engineered mutation |
Val 155 | Ala 155 | conflict |
Glu 162 | Gly 162 | engineered mutation |
Lys 206 | Ser 206 | engineered mutation |
Gly 207 | Cys 207 | engineered mutation |
Thr 208 | Cys 208 | engineered mutation |
Gly 209 | Pro 209 | engineered mutation |
Glu 237 | - | expression tag |
Asn 238 | - | expression tag |
Leu 239 | - | expression tag |
Tyr 240 | - | expression tag |
Phe 241 | - | expression tag |
Gln 242 | - | expression tag |
Gly 243 | - | expression tag |
His 244 | - | expression tag |
His 245 | - | expression tag |
His 246 | - | expression tag |
His 247 | - | expression tag |
His 248 | - | expression tag |
His 249 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 141548.4 | |
Non-Polymers* | Number of molecules | 54 |
Total formula weight | 5127.3 | |
All* | Total formula weight | 146675.7 |