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5OBG

Crystal structure of glycine binding protein in complex with strychnine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Soluble acetylcholine receptorpolymer24928309.75UniProt (Q8WSF8)
Pfam (PF02931)
Aplysia californica (California sea hare)
2CA, F, LA, Q, XA
(C, A, D, B, E)
STRYCHNINEnon-polymer334.45Chemie (SY9)
3BA, BB, CB, DB, EA...
(C, E, A, D, B)
1,2-ETHANEDIOLnon-polymer62.131Chemie (EDO)
4IA, K, TA, UA, W
(C, A, D, E, B)
SODIUM IONnon-polymer23.05Chemie (NA)
5AA, AB, JA, L, NA...
(C, E, A, D, B)
ACETATE IONnon-polymer59.09Chemie (ACT)
6DA, MA, R, YA
(C, D, B, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
7HB, IB, JB, KB, LB
(A, B, C, D, E)
waterwater18.0749Chemie (HOH)
Sequence modifications
A, B, C, D, E: 1 - 236 (UniProt: Q8WSF8)
PDBExternal DatabaseDetails
Phe 53Thr 53engineered mutation
Val 60Ala 60conflict
Arg 74Gln 74engineered mutation
Ala 110Tyr 110engineered mutation
Ser 135Ile 135engineered mutation
Val 155Ala 155conflict
Glu 162Gly 162engineered mutation
Lys 206Ser 206engineered mutation
Gly 207Cys 207engineered mutation
Thr 208Cys 208engineered mutation
Gly 209Pro 209engineered mutation
Glu 237-expression tag
Asn 238-expression tag
Leu 239-expression tag
Tyr 240-expression tag
Phe 241-expression tag
Gln 242-expression tag
Gly 243-expression tag
His 244-expression tag
His 245-expression tag
His 246-expression tag
His 247-expression tag
His 248-expression tag
His 249-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight141548.4
Non-Polymers*Number of molecules54
Total formula weight5127.3
All*Total formula weight146675.7
*Water molecules are not included.

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PDB entries from 2024-11-20

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