5OAL
Crystal structure of mutant AChBP in complex with strychnine (T53F, Q74R, Y110A, I135S, G162E)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Soluble acetylcholine receptor | polymer | 249 | 28355.8 | 15 | UniProt (Q8WSF8) Pfam (PF02931) In PDB | Aplysia californica (California sea hare) | |
2 | K, L, M, N, A... | STRYCHNINE | non-polymer | 334.4 | 15 | Chemie (SY9) | |||
3 | N | ARGININE | non-polymer | 175.2 | 1 | Chemie (ARG) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O: 1 - 236 (UniProt: Q8WSF8)
PDB | External Database | Details |
---|---|---|
Phe 53 | Thr 53 | engineered mutation |
Val 60 | Ala 60 | conflict |
Arg 74 | Gln 74 | engineered mutation |
Ala 110 | Tyr 110 | engineered mutation |
Ser 135 | Ile 135 | engineered mutation |
Val 155 | Ala 155 | conflict |
Glu 162 | Gly 162 | engineered mutation |
Glu 237 | - | expression tag |
Asn 238 | - | expression tag |
Leu 239 | - | expression tag |
Tyr 240 | - | expression tag |
Phe 241 | - | expression tag |
Gln 242 | - | expression tag |
Gly 243 | - | expression tag |
His 244 | - | expression tag |
His 245 | - | expression tag |
His 246 | - | expression tag |
His 247 | - | expression tag |
His 248 | - | expression tag |
His 249 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 425336.6 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 5191.4 | |
All* | Total formula weight | 430528.0 |