Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5OAL

Crystal structure of mutant AChBP in complex with strychnine (T53F, Q74R, Y110A, I135S, G162E)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
K	0004888	molecular_function	transmembrane signaling receptor activity
K	0005216	molecular_function	monoatomic ion channel activity
K	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
K	0006811	biological_process	monoatomic ion transport
K	0016020	cellular_component	membrane
K	0034220	biological_process	monoatomic ion transmembrane transport
L	0004888	molecular_function	transmembrane signaling receptor activity
L	0005216	molecular_function	monoatomic ion channel activity
L	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
L	0006811	biological_process	monoatomic ion transport
L	0016020	cellular_component	membrane
L	0034220	biological_process	monoatomic ion transmembrane transport
M	0004888	molecular_function	transmembrane signaling receptor activity
M	0005216	molecular_function	monoatomic ion channel activity
M	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
M	0006811	biological_process	monoatomic ion transport
M	0016020	cellular_component	membrane
M	0034220	biological_process	monoatomic ion transmembrane transport
N	0004888	molecular_function	transmembrane signaling receptor activity
N	0005216	molecular_function	monoatomic ion channel activity
N	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
N	0006811	biological_process	monoatomic ion transport
N	0016020	cellular_component	membrane
N	0034220	biological_process	monoatomic ion transmembrane transport
O	0004888	molecular_function	transmembrane signaling receptor activity
O	0005216	molecular_function	monoatomic ion channel activity
O	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
O	0006811	biological_process	monoatomic ion transport
O	0016020	cellular_component	membrane
O	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SY9 A 401

Chain	Residue
A	GLU162
A	TRP164
A	TYR205
B	PHE53
B	TYR72
B	ARG74
B	SER135
B	SER184

site_id	AC2
Number of Residues	6
Details	binding site for residue SY9 C 401

Chain	Residue
B	TRP164
B	TYR205
C	TYR72
C	SER135
C	SER184
B	GLU162

site_id	AC3
Number of Residues	8
Details	binding site for residue SY9 C 402

Chain	Residue
C	GLU162
C	TRP164
C	TYR205
C	TYR212
D	PHE53
D	ARG74
D	SER135
D	SER184

site_id	AC4
Number of Residues	8
Details	binding site for residue SY9 D 401

Chain	Residue
D	GLU162
D	TRP164
D	TYR205
E	PHE53
E	TYR72
E	ARG74
E	SER135
E	SER184

site_id	AC5
Number of Residues	8
Details	binding site for residue SY9 E 401

Chain	Residue
A	PHE53
A	TYR72
A	SER135
A	SER184
E	GLU162
E	SER163
E	TRP164
E	TYR205

site_id	AC6
Number of Residues	7
Details	binding site for residue SY9 G 401

Chain	Residue
F	GLU162
F	TRP164
F	TYR205
G	PHE53
G	TYR72
G	SER135
G	SER184

site_id	AC7
Number of Residues	6
Details	binding site for residue SY9 H 301

Chain	Residue
G	GLU162
G	TRP164
H	PHE53
H	TYR72
H	ARG74
H	SER135

site_id	AC8
Number of Residues	8
Details	binding site for residue SY9 H 302

Chain	Residue
H	GLU162
H	SER163
H	TRP164
H	TYR205
I	PHE53
I	TYR72
I	ARG74
I	SER184

site_id	AC9
Number of Residues	9
Details	binding site for residue SY9 I 301

Chain	Residue
I	GLU162
I	SER163
I	TRP164
I	TYR205
I	TYR212
J	PHE53
J	TYR72
J	ARG74
J	SER135

site_id	AD1
Number of Residues	8
Details	binding site for residue SY9 J 401

Chain	Residue
F	PHE53
F	TYR72
F	ARG74
F	SER184
J	GLU162
J	TRP164
J	TYR205
J	TYR212

site_id	AD2
Number of Residues	8
Details	binding site for residue SY9 K 401

Chain	Residue
K	GLU162
K	TRP164
K	TYR205
K	TYR212
L	PHE53
L	ARG74
L	SER135
L	SER184

site_id	AD3
Number of Residues	5
Details	binding site for residue SY9 K 402

Chain	Residue
K	PHE53
K	TYR72
K	SER184
O	TRP164
O	TYR205

site_id	AD4
Number of Residues	8
Details	binding site for residue SY9 L 401

Chain	Residue
L	GLU162
L	SER163
L	TRP164
L	TYR205
M	PHE53
M	TYR72
M	SER135
M	SER184

site_id	AD5
Number of Residues	9
Details	binding site for residue SY9 M 401

Chain	Residue
M	TRP164
M	TYR205
M	TYR212
N	PHE53
N	TYR72
N	SER135
N	SER184
M	GLU162
M	SER163

site_id	AD6
Number of Residues	4
Details	binding site for residue ARG N 301

Chain	Residue
E	TYR205
E	SER206
E	PRO209
N	ARG224

site_id	AD7
Number of Residues	9
Details	binding site for residue SY9 N 302

Chain	Residue
N	GLU162
N	SER163
N	TRP164
N	TYR205
N	TYR212
O	PHE53
O	TYR72
O	ARG74
O	SER184

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)