5O7I
ERK5 in complex with a pyrrole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 7 | polymer | 358 | 41057.2 | 1 | UniProt (Q13164) Pfam (PF00069) | Homo sapiens (Human) | MAPK 7,Big MAP kinase 1,BMK-1,Extracellular signal-regulated kinase 5,ERK-5 |
| 2 | B (A) | 4-(2-bromanyl-6-fluoranyl-phenyl)carbonyl-~{N}-pyridin-3-yl-1~{H}-pyrrole-2-carboxamide | non-polymer | 388.2 | 1 | Chemie (9N8) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 46 - 402 (UniProt: Q13164)
| PDB | External Database | Details |
|---|---|---|
| Gly 45 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41057.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 466.3 | |
| All* | Total formula weight | 41523.6 |
