5O5P

Poliovirus type 3 (strain Saukett) stabilized virus-like particle in complex with the pocket factor compound GPP3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (1)	Capsid proteins, VP1	polymer	300	33562.8	1	UniProt (Q84895) Pfam (PF00073)	Human poliovirus 3
2	B (2)	Capsid proteins, VP2	polymer	271	30189.0	1	UniProt (Q84895) Pfam (PF00073)	Human poliovirus 3
3	C (3)	Capsid proteins, VP3	polymer	238	26315.1	1	UniProt (Q84895) Pfam (PF00073)	Human poliovirus 3
4	D (4)	Capsid proteins, VP4	polymer	69	7452.1	1	UniProt (Q84895) Pfam (PF02226) UniProt (by SIFTS) (P03302)	Human poliovirus 3
5	E (1)	1-[5-[4-(ethoxyiminomethyl)phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazol-2-one	non-polymer		408.5	1	Chemie (9LW)

Sequence modifications

1: 1 - 300 (UniProt: Q84895)

PDB	External Database	Details
Met 105	Thr 683	engineered mutation
Leu 132	Phe 710	engineered mutation

2: 1 - 271 (UniProt: Q84895)

PDB	External Database	Details
Ile 18	Leu 87	engineered mutation
Met 215	Leu 284	engineered mutation
Glu 241	Asp 310	engineered mutation

3: 1 - 238 (UniProt: Q84895)

PDB	External Database	Details
Tyr 19	His 359	engineered mutation
Phe 85	Leu 425	engineered mutation

4: 1 - 69 (UniProt: Q84895)

PDB	External Database	Details
Ala 67	Unk 67	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97519.0
Non-Polymers*	Number of molecules	1
	Total formula weight	408.5
All*	Total formula weight	97927.5

*Water molecules are not included.