5O5E
Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with tunicamycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | polymer | 409 | 46173.7 | 1 | UniProt (Q9H3H5) Pfam (PF00953) Pfam (PF21383) | Homo sapiens (Human) | GlcNAc-1-P transferase,GPT,N-acetylglucosamine-1-phosphate transferase |
| 2 | B (A) | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE | non-polymer | 747.0 | 1 | Chemie (P6L) | |||
| 3 | C (A) | Tunicamycin | non-polymer | 830.9 | 1 | Chemie (9LH) | |||
| 4 | D (A) | UNKNOWN LIGAND | non-polymer | 1464.0 | 1 | Chemie (UNL) | |||
| 5 | E (A) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 1 - 408 (UniProt: Q9H3H5)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Gly 264 | Val 264 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46173.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 3041.9 | |
| All* | Total formula weight | 49215.7 |
