5O4O
HER3 in complex with Fab MF3178
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MF3178 FAB light chain | polymer | 214 | 23283.8 | 1 | Homo sapiens | ||
| 2 | B | MF3178 FAB heavy chain | polymer | 250 | 26981.5 | 1 | Homo sapiens | ||
| 3 | C | Receptor tyrosine-protein kinase erbB-3 | polymer | 649 | 71601.3 | 1 | UniProt (P21860) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) In PDB | Homo sapiens (Human) | Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3 |
| 4 | D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
C: 1 - 643 (UniProt: P21860)
| PDB | External Database | Details |
|---|---|---|
| His 644 | - | expression tag |
| His 645 | - | expression tag |
| His 646 | - | expression tag |
| His 647 | - | expression tag |
| His 648 | - | expression tag |
| His 649 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 121866.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 123600.2 |
