5O4F
Structure of GluK3 ligand-binding domain (S1S2) in complex with the agonist LM-12b at 2.10 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Glutamate receptor ionotropic, kainate 3 | polymer | 258 | 29092.5 | 2 | UniProt (P42264) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluK3,Glutamate receptor 7,GluR7 |
| 2 | C, D, E, F, N (B, A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 3 | G, O (B, A) | (3~{a}~{R},4~{S},6~{a}~{R})-1-methyl-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-c]pyrazole-3,4-dicarboxylic acid | non-polymer | 213.2 | 2 | Chemie (8VE) | |||
| 4 | H, I, J, P, Q... (B, A) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | K, L, M, S, T (B, A) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | U (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | V, W (B, A) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
B, A: 2 - 116 (UniProt: P42264)
B, A: 119 - 256 (UniProt: P42264)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Pro 0 | - | cloning artifact |
| Gly 1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58184.9 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1515.6 | |
| All* | Total formula weight | 59700.5 |
