5O45

Structure of human PD-L1 in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Programmed cell death 1 ligand 1	polymer	129	14792.9	1	UniProt (Q9NZQ7) Pfam (PF07686)	Homo sapiens (Human)	Programmed death ligand 1,B7 homolog 1,B7-H1
2	B (B)	PHE-MEA-9KK-SAR-ASP-VAL-MEA-TYR-SAR-TRP-TYR-LEU-CCS-GLY-NH2	polymer	15	1813.1	1		Synthetic construct
3	C, D (A, B)	water	water		18.0	338	Chemie (HOH)

Sequence modifications

A: 17 - 134 (UniProt: Q9NZQ7)

PDB	External Database	Details
Ala 135	-	expression tag
Ala 136	-	expression tag
Ala 137	-	expression tag
Leu 138	-	expression tag
Glu 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	16606.0
All*	Total formula weight	16606.0

*Water molecules are not included.