5O3C
Human Brd2(BD2) mutant in complex with 9-Me
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 2 | polymer | 114 | 13361.4 | 1 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | B (A) | methyl (2~{R})-2-[(4~{S})-6-(4-chlorophenyl)-9-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]propanoate | non-polymer | 424.9 | 1 | Chemie (9J2) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol | non-polymer | 134.2 | 1 | Chemie (DQW) | |||
| 5 | E (A) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A: 344 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Ser 342 | - | expression tag |
| Met 343 | - | expression tag |
| Val 383 | Leu 383 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13361.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 594.5 | |
| All* | Total formula weight | 13955.9 |
