5O32
The structure of complement complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E | Complement C3 | polymer | 645 | 71393.3 | 2 | UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) In PDB | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 2 | B, F | Complement C3 | polymer | 915 | 104073.2 | 2 | UniProt (P01024) Pfam (PF07677) Pfam (PF01759) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) Pfam (PF21308) In PDB | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 3 | C, G | Complement factor H,Complement factor H | polymer | 383 | 42767.1 | 2 | UniProt (P08603) Pfam (PF00084) In PDB | Homo sapiens (Human) | H factor 1,H factor 1 |
| 4 | D, H | Complement factor I | polymer | 321 | 35963.1 | 2 | UniProt (P05156) Pfam (PF21286) Pfam (PF21287) Pfam (PF00530) Pfam (PF00057) In PDB | Homo sapiens (Human) | C3B/C4B inactivator |
| 5 | I, J | Complement factor I | polymer | 244 | 27622.4 | 2 | UniProt (P05156) Pfam (PF00089) In PDB | Homo sapiens (Human) | C3B/C4B inactivator |
| 6 | K, M | beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G89225LT) | |||
| 7 | L, N | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | A, D, E, H | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 9 | H, J, D, I | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 10 | J | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) |
Sequence modifications
C, G: 19 - 264 (UniProt: P08603)
C, G: 1107 - 1230 (UniProt: P08603)
C, G: 1107 - 1230 (UniProt: P08603)
| PDB | External Database | Details |
|---|---|---|
| Lys 265 | - | linker |
| Gly 1095 | - | linker |
| Gly 1096 | - | linker |
| Gly 1097 | - | linker |
| Gly 1098 | - | linker |
| Gly 1099 | - | linker |
| Gly 1100 | - | linker |
| Gly 1101 | - | linker |
| Gly 1102 | - | linker |
| Gly 1103 | - | linker |
| Gly 1104 | - | linker |
| Gly 1105 | - | linker |
| Gly 1106 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 563638.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2670.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2997.0 | |
| All* | Total formula weight | 569305.5 |
