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5O26

Crystal structure of WNK3 kinase domain in a diphosphorylated state and in complex with AMP-PNP/Mg2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BSerine/threonine-protein kinase WNK3polymer28432685.72UniProt (Q9BYP7)
Pfam (PF00069)
In PDB
Homo sapiens (Human)Protein kinase lysine-deficient 3,Protein kinase with no lysine 3
2A, BPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.22Chemie (ANP)
3A, BMAGNESIUM IONnon-polymer24.34Chemie (MG)
4A1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5waterwater18.0165Chemie (HOH)
Sequence modifications
A, B: 133 - 414 (UniProt: Q9BYP7)
PDBExternal DatabaseDetails
Ser 131-expression tag
Met 132-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65371.4
Non-Polymers*Number of molecules7
Total formula weight1171.7
All*Total formula weight66543.1
*Water molecules are not included.

222926

PDB entries from 2024-07-24

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