5NZO

Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 1-methyl-3-phenyl-1H-pyrazol-5-amine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	D-3-phosphoglycerate dehydrogenase	polymer	195	20952.1	2	UniProt (O43175) Pfam (PF00389) Pfam (PF02826) In PDB	Homo sapiens (Human)	3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase
2	B, A	2-methyl-5-phenyl-pyrazol-3-amine	non-polymer		173.2	2	Chemie (9EZ)
3		water	water		18.0	272	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41904.2
Non-Polymers*	Number of molecules	2
	Total formula weight	346.4
All*	Total formula weight	42250.6

*Water molecules are not included.