5NZ4
Complex of I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | neuraminidase | polymer | 388 | 42713.6 | 2 | UniProt (C6KQL9) Pfam (PF00064) UniProt (by SIFTS) (C3W6G3) | unidentified influenza virus | |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E (E) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | F, G, Q, R, V (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 5 | H, S (A, B) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 2 | Chemie (G39) | |||
| 6 | I, T, U (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 7 | J, K, L, M, N... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 8 | AA, Z (B, A) | water | water | 18.0 | 1072 | Chemie (HOH) |
Sequence modifications
A, B: 82 - 469 (UniProt: C6KQL9)
| PDB | External Database | Details |
|---|---|---|
| Val 223 | Ile 213 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85427.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1597.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2053.4 | |
| All* | Total formula weight | 89078.1 |
