5NXA
Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL)in complex with its products AICAR and fumarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Adenylosuccinate lyase | polymer | 487 | 55216.4 | 8 | Pfam (PF00206) Pfam (PF10397) UniProt (by SIFTS) (A0A384E0N4) | Homo sapiens neanderthalensis | ASL,Adenylosuccinase,ASase |
| 2 | I, L, Q, U, W... (A, B, D, F, G...) | N-{[5-AMINO-1-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-1H-IMIDAZOL-4-YL]CARBONYL}-L-ASPARTIC ACID | non-polymer | 454.3 | 6 | Chemie (SSS) | |||
| 3 | J, K, N, P, R... (A, B, C, D, E...) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 4 | M, S (B, E) | FUMARIC ACID | non-polymer | 116.1 | 2 | Chemie (FUM) | |||
| 5 | O, Z (C, H) | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | non-polymer | 338.2 | 2 | Chemie (AMZ) | |||
| 6 | AA, BA, CA, DA, EA... (A, B, C, D, E...) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 441731.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3917.9 | |
| All* | Total formula weight | 445649.4 |
