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5NX8

Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Adenylosuccinate lyasepolymer48755216.44Pfam (PF00206)
Pfam (PF10397)
UniProt (by SIFTS) (A0A384E0N4)
Homo sapiens neanderthalensis
2E, F, N, O, T
(A, C, D)
DI(HYDROXYETHYL)ETHERnon-polymer106.15Chemie (PEG)
3G, H, K, P, Q...
(A, B, C, D)
GLYCEROLnon-polymer92.17Chemie (GOL)
4I, J, L, M, R...
(A, B, C, D)
CHLORIDE IONnon-polymer35.59Chemie (CL)
5AA, BA, CA, Z
(B, C, D, A)
waterwater18.01191Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight220865.8
Non-Polymers*Number of molecules21
Total formula weight1494.3
All*Total formula weight222360.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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