5NWZ
FIBROBLAST GROWTH FACTOR RECEPTOR 4 KINASE DOMAIN (449-753) IN COMPLEX WITH IRREVERSIBLE LIGAND CGA159527
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor receptor 4 | polymer | 307 | 34368.7 | 2 | UniProt (P22455) Pfam (PF07714) | Homo sapiens (Human) | FGFR-4 |
| 2 | C, D (A, B) | ~{N}-[3-[2-(3,5-dimethoxyphenyl)ethyl]-1~{H}-pyrazol-5-yl]-2-(propanoylamino)benzamide | non-polymer | 422.5 | 2 | Chemie (9CT) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 449 - 753 (UniProt: P22455)
| PDB | External Database | Details |
|---|---|---|
| Gly 447 | - | expression tag |
| Pro 448 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68737.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 845.0 | |
| All* | Total formula weight | 69582.3 |
