5NS9
Crystal structure of the GluA2 LBD (L483Y-N754S-L758V) in complex with glutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2,Glutamate receptor 2 | polymer | 292 | 32344.0 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | C, D (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 3 | E (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 4 | F, G, H, I, N... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | J, K, L, P, Q (A, B) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 6 | M, R (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 7 | S, T (A, B) | water | water | 18.0 | 905 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
A, B: 120 - 264 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Met -27 | - | initiating methionine |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Leu -15 | - | expression tag |
| Val -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Arg -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Met -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Ser -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Asn -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Tyr 94 | Leu 504 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Ser 242 | Asn 775 | engineered mutation |
| Val 246 | Leu 779 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64688.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1582.3 | |
| All* | Total formula weight | 66270.3 |
