Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 1PE A 301 |
| Chain | Residue |
| A | LYS117 |
| A | HOH484 |
| A | HOH529 |
| A | HOH769 |
| A | GLU201 |
| A | GLN202 |
| A | LYS226 |
| A | SER228 |
| A | CYS261 |
| A | GLY262 |
| A | SER263 |
| A | 1PE302 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue 1PE A 302 |
| Chain | Residue |
| A | VAL6 |
| A | PHE49 |
| A | SER228 |
| A | SER229 |
| A | CYS261 |
| A | GLY262 |
| A | SER263 |
| A | 1PE301 |
| A | HOH412 |
| A | HOH514 |
| A | HOH595 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PG0 A 303 |
| Chain | Residue |
| A | LYS4 |
| A | VAL7 |
| A | LYS82 |
| A | ASP84 |
| A | PRO205 |
| A | HOH493 |
| A | HOH645 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG149 |
| A | HOH432 |
| A | HOH482 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | LYS21 |
| A | ARG203 |
| A | LYS204 |
| A | GLU260 |
| A | HOH473 |
| A | HOH664 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | ARG148 |
| A | TRP159 |
| A | ARG163 |
| A | HOH403 |
| A | HOH482 |
| A | HOH667 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | SER140 |
| A | LYS144 |
| A | ARG148 |
| A | HOH427 |
| A | HOH440 |
| A | HOH450 |
| A | HOH581 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 308 |
| Chain | Residue |
| A | GLU97 |
| A | ILE100 |
| A | ASP101 |
| B | HOH415 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 309 |
| Chain | Residue |
| A | ARG149 |
| A | HOH656 |
| B | GLU243 |
| B | GLN244 |
| B | HOH784 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 310 |
| Chain | Residue |
| A | LEU215 |
| A | HOH456 |
| B | ASP248 |
| B | HOH721 |
| B | HOH772 |
| site_id | AD2 |
| Number of Residues | 13 |
| Details | binding site for residue GLU A 311 |
| Chain | Residue |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| A | TYR220 |
| A | HOH495 |
| A | HOH507 |
| A | HOH512 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | ARG31 |
| B | HOH437 |
| B | HOH443 |
| B | HOH450 |
| B | HOH489 |
| B | HOH662 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | ASP139 |
| B | SER140 |
| B | LYS144 |
| B | ARG148 |
| B | HOH402 |
| B | HOH424 |
| B | HOH444 |
| B | HOH451 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 303 |
| Chain | Residue |
| B | THR9 |
| B | THR54 |
| B | VAL56 |
| B | GLU77 |
| B | HOH582 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 304 |
| Chain | Residue |
| B | VAL211 |
| B | GLY212 |
| B | GLY213 |
| B | LEU215 |
| B | HOH416 |
| B | ILE113 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residue GLU B 305 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | GLU193 |
| B | TYR220 |
| B | HOH440 |
| B | HOH498 |
| B | HOH519 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO89 | |
| B | SER142 | |
| B | THR143 | |
| B | GLU193 | |
| A | THR91 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| B | PRO89 | |
| B | THR91 | |
| B | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 | |
