5NQR
Potent inhibitors of NUDT5 silence hormone signaling in breast cancer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ADP-sugar pyrophosphatase | polymer | 219 | 24355.6 | 2 | UniProt (Q9UKK9) Pfam (PF00293) | Homo sapiens (Human) | 8-oxo-dGDP phosphatase,Nuclear ATP-synthesis protein NUDIX5,Nucleoside diphosphate-linked moiety X motif 5,hNUDT5,YSA1H |
| 2 | C, D, E (A) | 8-(dimethylamino)-1,3-dimethyl-7-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl]purine-2,6-dione | non-polymer | 395.4 | 3 | Chemie (958) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48711.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1186.2 | |
| All* | Total formula weight | 49897.4 |
