5NOO

Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP and Tomudex

Replaces:  4IQQ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thymidylate synthase	polymer	315	35855.9	4	UniProt (Q9Y052) Pfam (PF00303)	Caenorhabditis elegans
2	E, G, I, K (A, B, C, D)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	4	Chemie (UMP)
3	F, H, J, L (A, B, C, D)	TOMUDEX	non-polymer		458.5	4	Chemie (D16)
4	M, N, O, P (A, B, C, D)	water	water		18.0	84	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143423.6
Non-Polymers*	Number of molecules	8
	Total formula weight	3066.7
All*	Total formula weight	146490.3

*Water molecules are not included.