5NN2
The structure of the polo-box domain (PBD) of Plk1 in complex with Z228588490
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase PLK1 | polymer | 232 | 26755.5 | 1 | UniProt (P53350) Pfam (PF00659) In PDB | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
2 | A | (3~{R},5~{R})-1-[2,4-bis(fluoranyl)phenyl]-5-oxidanyl-pyrrolidine-3-carboxylic acid | non-polymer | 243.2 | 1 | Chemie (Z24) | |||
3 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A: 371 - 594 (UniProt: P53350)
PDB | External Database | Details |
---|---|---|
Gly 363 | - | expression tag |
Pro 364 | - | expression tag |
Leu 365 | - | expression tag |
Gly 366 | - | expression tag |
Ser 367 | - | expression tag |
Pro 368 | - | expression tag |
Glu 369 | - | expression tag |
Phe 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26755.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 243.2 | |
All* | Total formula weight | 26998.7 |