5NN2
The structure of the polo-box domain (PBD) of Plk1 in complex with Z228588490
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PLK1 | polymer | 232 | 26755.5 | 1 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | B (A) | (3~{R},5~{R})-1-[2,4-bis(fluoranyl)phenyl]-5-oxidanyl-pyrrolidine-3-carboxylic acid | non-polymer | 243.2 | 1 | Chemie (Z24) | |||
| 3 | C (A) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A: 371 - 594 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 363 | - | expression tag |
| Pro 364 | - | expression tag |
| Leu 365 | - | expression tag |
| Gly 366 | - | expression tag |
| Ser 367 | - | expression tag |
| Pro 368 | - | expression tag |
| Glu 369 | - | expression tag |
| Phe 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26755.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 243.2 | |
| All* | Total formula weight | 26998.7 |
