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5NKP

Crystal structure of the human KLHL3 Kelch domain in complex with a WNK3 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Kelch-like protein 3polymer29231529.52UniProt (Q9UH77)
Pfam (PF01344)
Homo sapiens (Human)
2C, D
(D, C)
Serine/threonine-protein kinase WNK3polymer111318.32UniProt (Q9BYP7)Homo sapiensProtein kinase lysine-deficient 3,Protein kinase with no lysine 3
3E
(A)
CITRIC ACIDnon-polymer192.11Chemie (CIT)
4F, G, H
(A, B)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5I, J, K
(A, B, C)
waterwater18.043Chemie (HOH)
Sequence modifications
A, B: 298 - 587 (UniProt: Q9UH77)
PDBExternal DatabaseDetails
Ser 296-expression tag
Met 297-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight65695.6
Non-Polymers*Number of molecules4
Total formula weight298.5
All*Total formula weight65994.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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