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5NKG

Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 3d

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ephrin type-A receptor 2polymer30634462.81UniProt (P29317)
Pfam (PF07714)
Homo sapiens (Human)Epithelial cell kinase,Tyrosine-protein kinase receptor ECK
2B
(A)
~{N}-(2-chloranyl-6-methyl-phenyl)-2-[[3-ethyl-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamidenon-polymer498.01Chemie (8ZK)
3C
(A)
waterwater18.0358Chemie (HOH)
Sequence modifications
A: 596 - 900 (UniProt: P29317)
PDBExternal DatabaseDetails
Gly 595-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34462.8
Non-Polymers*Number of molecules1
Total formula weight498.0
All*Total formula weight34960.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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