5NK7
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | B (A) | ~{N}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{R},4~{R})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | non-polymer | 488.0 | 1 | Chemie (8ZZ) | |||
| 3 | C (A) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34462.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 488.0 | |
| All* | Total formula weight | 34950.8 |
