5NJ9
E. coli Microcin-processing metalloprotease TldD/E with DRVY angiotensin fragment bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Metalloprotease TldD | polymer | 495 | 53091.6 | 2 | UniProt (P0AGG8) Pfam (PF01523) Pfam (PF19290) Pfam (PF19289) | Escherichia coli K-12 | |
| 2 | B, D (B, D) | Metalloprotease PmbA | polymer | 450 | 48421.5 | 2 | UniProt (P0AFK0) Pfam (PF01523) Pfam (PF19290) Pfam (PF19289) | Escherichia coli K-12 | Protein TldE |
| 3 | E, F (E, F) | ASP-ARG-VAL-TYR | polymer | 4 | 552.6 | 2 | UniProt (by SIFTS) (P01019) | Homo sapiens | |
| 4 | G, Q (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, K, R, U (A, B, C, D) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 4 | Chemie (MES) | |||
| 6 | I, L, M, N, O... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 7 | J, P, T, Z (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 8 | AA, BA, CA, DA, EA (A, B, C, D, E) | water | water | 18.0 | 2060 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 481 (UniProt: P0AGG8)
| PDB | External Database | Details |
|---|---|---|
| Met -13 | - | initiating methionine |
| Gly -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Ser -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Asp 401 | Gly 401 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 204131.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1624.4 | |
| All* | Total formula weight | 205755.6 |
