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5NHR

CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, CUBIC CRYSTAL FORM

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(L, B)
Bimagrumab Fv Light-Chainpolymer11912513.72Homo sapiens (Human)
2B, D
(H, A)
Bimagrumab Fv heavy-chainpolymer12113423.92Homo sapiens (Human)
3E, F
(C, D)
Activin receptor type-2Bpolymer9911646.92UniProt (Q13705)
Pfam (PF01064)
Homo sapiens (Human)Activin receptor type IIB,ACTR-IIB
Sequence modifications
C, D: 24 - 117 (UniProt: Q13705)
PDBExternal DatabaseDetails
Gly 19-expression tag
Pro 20-expression tag
Lys 21-expression tag
Ala 22-expression tag
Met 23-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight75169.1
All*Total formula weight75169.1
*Water molecules are not included.

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PDB entries from 2024-11-06

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