5NHG
Crystal structure of the human dihydrolipoamide dehydrogenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Dihydrolipoyl dehydrogenase, mitochondrial | polymer | 495 | 52506.0 | 8 | UniProt (P09622) Pfam (PF07992) Pfam (PF02852) | Homo sapiens (Human) | Dihydrolipoamide dehydrogenase,Glycine cleavage system L protein |
| 2 | I, L, M, P, Q... (A, B, C, D, E...) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 8 | Chemie (FAD) | |||
| 3 | J, K, N, R, S... (A, C, E, F, G) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 7 | Chemie (TRS) | |||
| 4 | O (C) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 5 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 474 (UniProt: P09622)
| PDB | External Database | Details |
|---|---|---|
| Ala -20 | - | expression tag |
| Ser -19 | - | expression tag |
| Trp -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| Pro -15 | - | expression tag |
| Gln -14 | - | expression tag |
| Phe -13 | - | expression tag |
| Glu -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 420047.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 7348.6 | |
| All* | Total formula weight | 427396.5 |
