5NF6

Structure of GluK3 ligand-binding domain (S1S2) in complex with CIP-AS at 2.55 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Glutamate receptor ionotropic, kainate 3,Glutamate receptor ionotropic, kainate 3	polymer	258	29092.5	2	UniProt (P42264) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (Rat)	GluK3,Glutamate receptor 7,GluR7,GluK3,Glutamate receptor 7,GluR7
2	B, A	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	B, A	(3~{a}~{S},4~{S},6~{a}~{R})-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-d][1,2]oxazole-3,4-dicarboxylic acid	non-polymer		200.1	2	Chemie (8VN)
4	B	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7		water	water		18.0	87	Chemie (HOH)

Sequence modifications

B, A: 2 - 116 (UniProt: P42264)

PDB	External Database	Details
Gly -1	-	cloning artifact
Pro 0	-	cloning artifact
Gly 1	-	cloning artifact

B, A: 119 - 256 (UniProt: P42264)

PDB	External Database	Details
Gly 117	-	linker
Thr 118	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58184.9
Non-Polymers*	Number of molecules	12
	Total formula weight	1071.4
All*	Total formula weight	59256.3

*Water molecules are not included.