5NEU
Localised Reconstruction of Integrin alpha V beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose B.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | 1 | O1 Manisa VP1 | polymer | 208 | 22850.9 | 1 | UniProt (Q6PMW3) Pfam (PF00073) In PDB | Foot-and-mouth disease virus | |
2 | 2 | O1 Manisa VP2 | polymer | 218 | 24417.5 | 1 | UniProt (Q6PMW3) Pfam (PF00073) In PDB | Foot-and-mouth disease virus | |
3 | 3 | Capsid protein | polymer | 220 | 23933.9 | 1 | UniProt (A0A1C6ZW60) Pfam (PF00073) UniProt (by SIFTS) (Q6PMW3) In PDB | Foot-and-mouth disease virus | |
4 | 4 | O1 Manisa VP4 | polymer | 85 | 8766.1 | 1 | UniProt (E1ACS1) Pfam (PF08935) UniProt (by SIFTS) (D1H101) In PDB | Foot-and-mouth disease virus | |
5 | A | Integrin alpha-V | polymer | 590 | 64937.8 | 1 | UniProt (P06756) Pfam (PF01839) Pfam (PF08441) In PDB | Homo sapiens (Human) | Vitronectin receptor subunit alpha |
6 | B | Integrin beta-6 | polymer | 470 | 51534.6 | 1 | UniProt (P18564) Pfam (PF00362) Pfam (PF18372) Pfam (PF17205) In PDB | Homo sapiens (Human) | |
7 | 1 | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
8 | B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
2: 1 - 218 (UniProt: Q6PMW3)
3: 1 - 220 (UniProt: A0A1C6ZW60)
A: 1 - 594 (UniProt: P06756)
B: 5 - 539 (UniProt: P18564)
PDB | External Database | Details |
---|---|---|
Tyr 93 | Ser 379 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 168 | Ala 471 | conflict |
Val 174 | Ala 477 | conflict |
PDB | External Database | Details |
---|---|---|
- | Ala 60 | deletion |
- | Ser 61 | deletion |
Cys 400 | Met 430 | conflict |
- | Gln 534 | deletion |
- | Lys 535 | deletion |
PDB | External Database | Details |
---|---|---|
Cys 249 | Ile 287 | conflict |
Asn 517 | His 469 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 196440.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 104.5 | |
All* | Total formula weight | 196545.2 |