5NEU

Localised Reconstruction of Integrin alpha V beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose B.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005198	molecular_function	structural molecule activity
1	0019028	cellular_component	viral capsid
2	0005198	molecular_function	structural molecule activity
3	0005198	molecular_function	structural molecule activity
4	0019030	cellular_component	icosahedral viral capsid
A	0007155	biological_process	cell adhesion
A	0008305	cellular_component	integrin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG 1 2001

Chain	Residue
1	ASP147
B	ASP102
B	SER104
B	GLU202
B	ALA234

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site_id	AC2
Number of Residues	5
Details	binding site for residue CA B 601

Chain	Residue
B	GLU202
B	GLU141
B	ASN197
B	ASP199
B	PRO201

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site_id	AC3
Number of Residues	4
Details	binding site for residue CA B 602

Chain	Residue
B	ASP109
B	ASP110
B	LYS317
B	ASP318

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Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CaChpGhmGPrC

Chain	Residue	Details
B	CYS527-CYS538

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: in MIDAS binding site => ECO:0000269|PubMed:25383667, ECO:0007744|PDB:4UM8

Chain	Residue	Details
B	ASP102
A	PHE294
A	ASP351
A	ASP353
A	PHE355
A	ASP357
A	ALA359
A	ASP415
A	ASN417
A	TYR419
A	ASP421
A	ASP234
A	ILE423
A	ILE236
A	ASP238
A	VAL240
A	ASN286
A	ASP288
A	TYR290
A	ASP292

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: in MIDAS binding site => ECO:0000269|PubMed:25383667, ECO:0007744|PDB:4UM8, ECO:0007744|PDB:4UM9

Chain	Residue	Details
B	SER104
B	GLU202

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: in MIDAS binding site => ECO:0000250|UniProtKB:P05106

Chain	Residue	Details
B	SER106
A	THR268
A	THR460
A	SER528

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: in ADMIDAS binding site => ECO:0000269|PubMed:25383667, ECO:0007744|PDB:4UM8, ECO:0007744|PDB:4UM9

Chain	Residue	Details
B	ASP109
B	ASP110

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: in LIMBS binding site => ECO:0000269|PubMed:25383667, ECO:0007744|PDB:4UM9

Chain	Residue	Details
B	GLU141
B	ASN197
B	ASP199
B	PRO201

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: in ADMIDAS binding site and liganded-open conformation => ECO:0000250|UniProtKB:P05106

Chain	Residue	Details
B	ASP233

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site_id	SWS_FT_FI7
Number of Residues	1
Details	BINDING: in ADMIDAS binding site and unliganded-closed conformation => ECO:0000269|PubMed:25383667, ECO:0007744|PDB:4UM8

Chain	Residue	Details
B	LYS317

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site_id	SWS_FT_FI8
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:25383667, ECO:0007744|PDB:4UM8, ECO:0007744|PDB:4UM9

Chain	Residue	Details
B	ASN26
B	ASN59
B	ASN436

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site_id	SWS_FT_FI9
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:25383667, ECO:0000269|PubMed:28117447, ECO:0007744|PDB:4UM8, ECO:0007744|PDB:4UM9

Chain	Residue	Details
B	ASN222

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site_id	SWS_FT_FI10
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
B	ASN445
B	ASN511
B	ASN519

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