5ND2
Microtubule-bound MKLP2 motor domain in the presence of ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Kinesin-like protein KIF20A | polymer | 501 | 56021.3 | 1 | UniProt (P97329) Pfam (PF00225) | Mus musculus (House Mouse) | Kinesin-like protein 174,Rab6-interacting kinesin-like protein,Rabkinesin-6 |
| 2 | B (A) | Tubulin alpha chain | polymer | 451 | 50107.2 | 1 | UniProt (F2Z4C1) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P81947) | Bos taurus (Bovine) | |
| 3 | C (B) | Tubulin beta-2B chain | polymer | 445 | 49907.8 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 4 | D (C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E, G (C, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 7 | H (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 8 | I (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) PubChem (16757828) PubChem (16760674) PubChem (4666) PubChem (21458255) PubChem (23307219) PubChem (23412627) PubChem (23636632) PubChem (16760177) PubChem (16742549) PubChem (24848897) PubChem (24867246) PubChem (21733096) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (44323108) PubChem (44356961) PubChem (44403716) PubChem (24754091) PubChem (24207713) PubChem (24791027) PubChem (25200067) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (46781469) PubChem (44279927) PubChem (44335735) PubChem (44291178) PubChem (44328863) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (49868078) PubChem (45489039) PubChem (46782671) PubChem (54259298) PubChem (71209844) PubChem (57908851) PubChem (57946364) PubChem (58803237) PubChem (53313247) PubChem (53298534) PubChem (54259297) PubChem (59844545) PubChem (54259299) PubChem (59904698) PubChem (60123443) PubChem (57489669) PubChem (57999380) PubChem (58460861) PubChem (58777027) PubChem (58798493) PubChem (58596717) PubChem (59048611) PubChem (59042813) PubChem (58877402) PubChem (60005248) PubChem (59873251) PubChem (59914794) PubChem (59919147) PubChem (60123436) PubChem (60011010) PubChem (60147315) PubChem (66795656) PubChem (70943371) PubChem (71096818) PubChem (5460441) PubChem (14060298) PubChem (176586897) PubChem (177678861) PubChem (73759783) PubChem (36314) PubChem (60915) PubChem (177409) PubChem (184492) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (441276) PubChem (9854162) PubChem (73707502) PubChem (73759704) PubChem (9897470) PubChem (10033513) PubChem (10485732) PubChem (11506104) PubChem (89493063) PubChem (11828953) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (14060309) PubChem (15983941) PubChem (91885464) PubChem (5317123) PubChem (5321715) PubChem (101920282) PubChem (5352019) PubChem (121459571) PubChem (122361554) PubChem (101598423) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (124747272) PubChem (124893098) PubChem (9875988) PubChem (126968948) PubChem (129395998) PubChem (129627423) PubChem (10748131) PubChem (132517454) PubChem (118528174) PubChem (11320430) PubChem (11354895) PubChem (134368714) PubChem (134972678) PubChem (124747271) PubChem (124747273) PubChem (124747274) PubChem (137705323) PubChem (138106885) PubChem (126761000) PubChem (140731501) PubChem (140512017) PubChem (133052515) PubChem (133640187) PubChem (146034004) PubChem (153289350) PubChem (154037993) PubChem (134715514) PubChem (155982214) PubChem (159121804) PubChem (160053861) PubChem (159716711) PubChem (160171678) PubChem (160585530) PubChem (163077211) PubChem (163077212) PubChem (163077209) PubChem (163284947) PubChem (143890766) PubChem (168322423) PubChem (152743329) PubChem (169917882) PubChem (171036874) PubChem (154828192) PubChem (144453087) PubChem (160585532) PubChem (175758871) PubChem (163077210) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (165084161) PubChem (166711459) PubChem (167423928) PubChem (170014955) PubChem (170362150) |
Sequence modifications
A: 1 - 451 (UniProt: F2Z4C1)
B: 1 - 455 (UniProt: Q6B856)
| PDB | External Database | Details |
|---|---|---|
| Ser 136 | Leu 136 | conflict |
| Gly 265 | Ile 265 | conflict |
| Glu 358 | Gln 358 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 55 | conflict |
| Val 172 | Met 170 | conflict |
| Ala 298 | Ser 296 | conflict |
| Val 318 | Ile 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 156036.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2296.1 | |
| All* | Total formula weight | 158332.4 |
