5ND2
Microtubule-bound MKLP2 motor domain in the presence of ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Kinesin-like protein KIF20A | polymer | 501 | 56021.3 | 1 | UniProt (P97329) Pfam (PF00225) | Mus musculus (House Mouse) | Kinesin-like protein 174,Rab6-interacting kinesin-like protein,Rabkinesin-6 |
| 2 | B (A) | Tubulin alpha chain | polymer | 451 | 50107.2 | 1 | UniProt (F2Z4C1) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P81947) | Bos taurus (Bovine) | |
| 3 | C (B) | Tubulin beta-2B chain | polymer | 445 | 49907.8 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 4 | D (C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | E, G (C, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 7 | H (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 8 | I (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) |
Sequence modifications
A: 1 - 451 (UniProt: F2Z4C1)
B: 1 - 455 (UniProt: Q6B856)
| PDB | External Database | Details |
|---|---|---|
| Ser 136 | Leu 136 | conflict |
| Gly 265 | Ile 265 | conflict |
| Glu 358 | Gln 358 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Thr 55 | conflict |
| Val 172 | Met 170 | conflict |
| Ala 298 | Ser 296 | conflict |
| Val 318 | Ile 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 156036.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2296.1 | |
| All* | Total formula weight | 158332.4 |
